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MCQ 3 - Pharmacology



A patient wakes up for an operation complaining of hearing loss in their left ear? Which drug is she likely to have received?

A) Ciprofloxacin
B) Benzylpenicillin
C) Gentamicin
D) Ceftazidime


Answer is C



Ototoxic medications include:


  • Aspirin
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Aminoglycosides (such as gentamicin, streptomycin, and neomycin)
  • Loop diuretics 
  • Drugs to treat cancer: Cyclophosphamide, Cisplatin, and Bleomycin.

 - Aspirin
 - Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen.
- Certain antibiotics, especially aminoglycosides (such as gentamicin, streptomycin, and neomycin). - Hearing-related side effects from these antibiotics are most common in people who have kidney disease or who already have ear or hearing problems.
Loop diuretics used to treat high blood pressure and heart failure, such as furosemide (Lasix) or bumetanide.
Medicines used to treat cancer, including cyclophosphamide, cisplatin, and bleomycin.
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